| Company Name | Category | Employment |
| Halliburton Services | Oilfield Services | 705 |
| Kilgore Independent School District | Primary & Secondary Public Education | 606 |
| General Dynamics SATCOM | Satellite Communication Equipment | 550 |
| Kilgore College | Higher Education Institute | 363 |
| Region VII Education Service Center | Regional Public Education Service Provider | 290 |
| Martin Midstream Partners, LP | Mkt. & Transporting of Petroleum/Chemicals | 241 |
| Exterran | Compression Services | 197 |
| Closure Systems International, Inc. | Plastic Containers | 227 |
| Caterpillar | Mining Equipment | 184 |
| Pak-Sher Company | Plastic Bags | 160 |
| Orgill, Inc. | Warehouse Distribution | 178 |
| City of Kilgore | Municipal Government | 155 |
| BJ Services | Oilfield Services | 155 |
| Skeeter Products, Inc. | Recreational | 151 |
| Weatherford International | Oil & Gas Services | 112 |
| Triumph Group, Inc. | Machined Aircraft Parts, Misc. Trans. Equip. | 105 |
| Baker Petrolite | Oil & Gas Services | 105 |
| Allied Waste Services | Solid Waste Management | 92 |
| Cudd Pressure Control | Oilfield Services | 225 |
| Frank's Casing Crew & Rental Tools, Inc. | Oilfield Services | 83 |
| Ana-Lab Corp. | Analytical Services | 68 |
| IESI, TX Corp. | District Headquarters, Waste Collection, Transportation and Disposal | 62 |